The IN-SITU One Health Problem-Based Learning for Animal and Ecosystem Health was held this year for the fifth time from 19th to 21st April 2019 in Akademi Pengembangan Veterinar and Pusat Perkhidmatan Veterinar Jerangau in Terengganu. With the objective of the activity to expose students to the application of the theories learned in class at the pre-clinical level to the problem investigation used by the One Health concept, a total of 33 students from various backgrounds, each is contributing to the unique aspect of One Health. Five triggers were introduced, and participants were required to discuss the triggers and fill up a FILA (Fact, Idea, Learning Issue, Action) table to organized ideas and thoughts to investigate the problem. Although the program was only for two days, the experiences gained during those days were priceless. Positive feedbacks were received from participants, facilitators, and the staffs in the academy and center.